Does the RTRI detect acute HIV infection?

No. The RTRI does not detect acute HIV infection before antibody response. Persons who have acute HIV infection do not have HIV antibodies and will test HIV-negative by a national HIV testing algorithm comprised of HIV antibody tests.  Thus, in countries where the national HIV testing algorithm includes HIV antibody tests, persons with acute infection will not be detected and will not be referred for recent infection testing by the RTRI.