Research & Publications

Estimating HIV Incidence and Detecting Recent Infection among Pregnant Adolescent Girls and Young Women in Malawi – Working Together for an AIDS-free Future for Girls and Women (October 2019)

The Malawi Ministry of Health (MOH) and its partners implemented a novel surveillance system to detect and characterize recent HIV infections and estimate HIV incidence among adolescent girls and young women (AGYW) receiving antenatal care (ANC) in four high-prevalence districts of Malawi. A description of the methods and key findings from the pilot implementation of this surveillance system – which was called the Malawi Recency Study.

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Tracking with recency assays to control the epidemic: real-time HIV surveillance and public health response (July 2019)

With new developments in laboratory technology, rapid detection of recent HIV infection (i.e. HIV-antibody seroconversion occurring on average in the past 6 months) is now possible using a validated rapid test for recent infection (RTRI) that diagnoses HIV and detects recent infection within minutes [4–6]. The RTRI allows person, place, and time to be described for all new HIV diagnoses at the point of HIV testing services (HTS), forming the basis of a real-time surveillance and public health response system that accelerates the surveillance to care continuum. As the system generates routine information on trends in new diagnoses, it can simultaneously provide signals at the most granular level to inform programs where to focus interventions to reach those that need them the most.

MeSH Consortium Report on the feasibility and utility of HIV recent infection testing in a range of routine service provision contexts (July 2019)

Distinguishing recently acquired infection from “long-standing” infection among persons newly diagnosed with HIV can help identify populations and geographic areas where current transmission is occurring; crucial information to inform programme planning. Given this, we set out to assess the feasibility and utility of various approaches to conducting HIV recent infection testing in a range of routine service-provision contexts; namely, in antenatal clinics providing PMTCT services (Siaya County, Kenya), routine HIV testing and counselling clinics (Nairobi, Kenya), and a programme for female sex workers (Zimbabwe).